The side effects for the Prolia are as bad or even worse than the Lupron. We have contributors from all over the world. However he wasn't in practice at that time. I have 60 titanium staples holding mine in place. I was advised to not do a biopsy at that time by my GP unless they did an ultrasound and it showed an area of concern. This is a natural reaction, however it is a wrongful one, since the side effects from these radical treatments are very substantial. The biopsy followed and it was positive in all needles. I read with interest your cross discussion with Hopeful above. MY GP Suggested a different doctor. Lesions on MRI were assigned a PIRADS score and comparison made with histopathology results. So, the Lupron caused leg muscle and bone and joint pain on top of the arthritis. Whatever decision you may take, please do not rush. They always keep it real and make sure I understand that the cancer could and probably will come back at some later time. For women with lobular breast cancer a breast MRI scan might be used to see the cancer. The tendency is to think that cancer is of someone else. Tony, you do not know if or if not you have any cancer at this time, but if you are diagnosed with a low aggressive, low volume disease this can be a consideration. But no amount of speculating, no amount of worry or imagining, will give you definitive answers. Even after the results of the biopsy, there are cancers (Gleason score measures aggressiveness) that are indolent, that is not likely to spread.....this is fairly common, and can very well happen in your case.....it may be  a good idea for you to do research about "Gleason Scores" at this point. I could really fly. The results for MRI prostate cancer detection are shown in this table: MRI specificity (correctly identified presence … My favorite English musician is the semi-retired Jeff Lynn, founder of ELO. It can take up to an hour and a half. So, Please be aware that this problem could come about. they were big in the UK in the 70's....as I'm writing this I'm listening to the radio and there is currently an interview with their guitarist Wilko Johnson who was diagnosed with late stage pancreatic cancer 3 years ago,  he chose not to receive chemo.....He is now "cured" and has resumed his music career, played last year at Glastonbury, made an album with Roger Daltrey from "The Who" and so on.....Gives everyone a bit of hope I guess. As long as my PSA stays at "0", they tell me I'm doing well. We already have plans talked through if that occurs. That's still very low. In 2010 I read a Chinese clinical study done by researchers in China that managed some evidence comparing image studies with post biopsy findings. I have no idea why....it is from Adele; the line goes and it's round and around and around and around we go..... Hi Max, I don't know if the "round and around etc." Symptoms would rule an intervention which could occur after many years of quality living (avoiding the risks from treatments). Hi Will, thanks for your post.....You appear to have been "through the mill" Sorry to hear that.....I'm likewise a keen cyclist although not a serious one....I haven't been out on the bike since all this madness began around 7 weeks ago, I haven't had the gumption.....I think I'm frightened of looking too slim in case I then convince myself that I'm losing weight due to something else.....It's amazing how suggestible we humans can be....we think we are sophisticated beings until faced with our own mortatility and then we become as superstitious as neanderthal man (or is it just me? Hi Will, Now you're aware of Dr Feelgood, you'll probably keep hearing them "ad nauseum" from now on ....Synchronicity..... How wonderful that your former pupils are helping you out in regards to your health problems.....Just as well you were nice to them, or you could find yourself getting biopsied on a weekly basis, Thanks for the "Heads Up" but I don't think melanoma should be a problem for me, I'm of Italian descent, so have very dark olive skin....never had to worry about the sun in the past.....But never say never I suppose....Don't need to be baiting the "Cancer Gods", Hope your Melanoma stays in remission (good word that). Our cancer detection rate, while using different methods in tandem, surpasses that from using either method alone. I kept it "light" and that made them happy as well. That's what they told me. So, Let the Music Play, let the Wine (or whatever) Flow, Get out there a drive your pants off in your favorite sports or muscle car, enjoy nature, and live every day like it's your last. Magnetic resonance imaging (MRI) can definitively diagnose around 90 percent of all breast cancers, compared to only 37.5 percent detection rate for the combined methods of mammography and ultrasound. Several live performances in the set. Then Dr. Miller had the robot do a mirror image and it got to the lymph nodes on the left side. These can predict the clinical stage (advancement) of a positive case. That was the area where the radiation had hit. About 70 percent of cancer in those men was found using the combination method. So, the radioactive treatments woudln't have worked. Please consult your healthcare provider with any questions or concerns you may have regarding your condition. I say that I thought that a 3T MRI could tell the difference between something nasty, something benign or inflammation....He says that this is not the case, his words were something like: "PSA means nothing, Free PSA means nothing, Scan means nothing only a biopsy can see what this is" He did say that if I wasn't worried I could leave it until the next PSA reading to see what has happened, but I don't have that kind of personality. ....Hospital appointment yesterday to discuss results with urology dept. When I am waiting for the results of my tests or have to make a decision now my level of apprehension is a one or two out of ten...........When I was diagnosed my level was 30 on a 10 point scale. Although important the PSA can be looked at, only  as a trend, the individual points can be affected by a multitude of things: inflamation, sex before the PSA, exercise (especially bike riding) before the PSA, a digital rectal exam or massage before the PSA..even a hard stool. I plan to continue with this treatment option for the rest of my life if I can. While the remaining 52 men had no visible lesions, the researchers still found cancer in 15 percent of them using the traditional ultrasound test. Perhaps I should change my moniker here to hopeless and pessimistic, I don't know if I could do the active surveillance thing....I don't think I have that kind of personality glad it's working for you, Good luck with the biopsy, hope it all works out for you. We are the good ones and have done nothing bad. He did a DRE and told me I had the smallest Prostate he had ever examined. This guy is a well known Professor of urology with an international reputation, many books and papers published etc....40 minute consultation and DRE and he tells me "No Cancer"....."Great" I thought and skipped off.....I was happy to call it a day and cancel the upcoming hospital appointments My wife although pleased had other ideas and insisted I stick with the program. This thread has become unexpectedly interesting for music people; I am one of  them, but don't play anything (except CDs). However, if a sample is taken from these tissues (guided biopsy) and found by a pathologist to be cancerous then the patient would be declared positive and the image exam would provide the extend (size) of the tumour. I about fell off the exam table. Endoscopy. Thank you in advance          Tony. Active Surveillance does not prejudice the benefit of a future treatment. (he isn't the consultant obviously) I explain my reason and he asks to see the lowered test results, I show him. My last three check ups have been clean with no surgery needed. My dad had red hair. Canvey Island was a port where Oil Tankers would pull in and offload their cargo to the local refineries.....It was a very bleak industrial part of the country...then fallen on hard times, which of course is always a good breeding ground for disaffected youth making Rock & Roll....I've looked at the you tube clip of Milk and Alcohol and can only see one version....If it's the same one you've seen then Wilko Johnson had left by then, There was an acrimonious break up in 1978. I went to him , and again my DRE didn't show much of a problem. Many times I'd let it there, but sometimes change to Jazz or Blues, depending on my state of mind that day. At 6 weeks I couldn't take it any more and bugged the hell out of him and ask him If I could try my trainer/spinner bike. This systematic sextant extended biopsy approach samples approximately 0.04% of the prostate volume and yields cancer detection rates of only up to 40%. Sorry to hear of your concerns. I now feel like I have shot myself in the foot as I have now booked a biopsy for 2 weeks time and the results 2 weeks after that, so instead of finding out yesterday I now have another 4 weeks to sweat before I get a (maybe) definitive answer.......Basically my question is this: Has anybody had the experience where an MRI scan has shown up something which turned out to be nothing to worry about....or is the doc just not being 100% straight with me? My Hernias popped out while I was carrying a ladder down a flight of steps from the back sun deck on the house. ", Hi H&O....Interesting statistics, obviously you had very low involvement, and got onto a research project, and they seem to be throwing all manner of tests your way.....I'm glad that it is all working out right for you....I'm 8 years younger than you were when you got your diagnosis (nice birthday present) not that that makes any difference.....66 is the new 40 right?......Maybe if the docs were to give me a 25 year guarantee along with the free servicing I might (only might) sign on the dotted line......I wonder that when you're going for one of your regular scans, psa tests etc. It helped, I think. This technique does not utilize ionizing radiations such as X-rays. Turned out that was not the problem. When it comes to detecting breast cancer, a new study published in JAMA finds there's a technique that's even more effective than 3D mammography. The rest of that night I was at the hospital. 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